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KMID : 1138520200230020079
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Journal of Pharmacopuncture
2020 Volume.23 No. 2 p.79 ~ p.87
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Variations in Ginsenosides of Raw Ginseng According to Heating Temperature and Time
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Kim Chan-Joong
Kim Bo-Mi
Kim Cheon-Suk
Baek Jung-Yeon
Jung In-Chan
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Abstract
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Objectives: Ginsenosides found in ginseng, and the hydrolysates derived from their conversion, exhibit diverse pharmacological characteristics [1]. These have been shown to include anti-cancer, anti-angiogenic, and anti-metastatic effects, as well as being able to provide hepatic and neuroprotective effects, immunomodulation, vasodilation, promotion of insulin secretion, and antioxidant activity. Therefore, the purpose of this study was to examine how quickly the ginsenosides decompose and what kinds of degradation products are created under physicochemical processing conditions that don’t involve toxic chemicals or other treatments that may be harmful.
Methods: The formation of ginsenoside-Rg2 and ginsenoside-Rg3 was examined. These demonstrated diverse pharmacological effects.
Results: We also investigated physicochemical factors affecting their conversion. The heating temperatures and times yielding the highest concentration of ginsenosides (-Rb1, -Rb2, -Rc, -Rd, -Rf, -Rg1, and ?Re) were examined. Additionally, the heating temperatures and rates of conversion of these ginsenosides into new ‘ginseng saponins’ , were examined.
Conclusion: In conclusion, obtained provide us with effective technology to control the concentration of both ginsenosides and the downstream converted saponins (ginsenoside-Rg2, Rg3, Rg5, and Rk1 etc.), as well as identifying the processing conditions which enable an enrichment in concentration of these compounds.
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KEYWORD
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ginseng, ginsenosides, heating temperature, hydrolysis, physicochemical factor
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